Tresa McGranahan

BIOGRAPHY

Dr. Tresa McGranahan completed her PhD in molecular neurobiology at the Salk Institute studying the role of high affinity nicotinic receptors in memory and behavior. She then completed post doctoral research in neuroimmunology at Stanford University during neurology residency and Neuro Oncology fellowship. She is currently a neuro-oncologist at the University of Washington/Seattle Cancer Care Alliance. Her clinical and research work focus on patients with brain tumors as well as neurologic complications of cancer.

 

Abstract

Tumor treating fields (TTF) are an emerging use of noninvasive electrical therapy for the treatment of solid tumors. Alternating electrical fields are used in TTF to inhibit tumor cell division by preventing normal polymerization of mitotic spindles and also impairing the cleavage site of dividing cell. Different tumor cell lines have maximal effect at variable frequencies of TTF in the range of 100-300kHz.  Clinically, TTF have been shown to increase local tumor control for newly diagnosed glioblastoma, recurrent glioblastoma and mesothelioma. There are ongoing clinical trials for many solid malignancies including pancreatic adenocarcinoma, hepatocellular carcinoma, meningioma and lung cancer. Electrical therapy has transformed the treatment of glioblastoma and will likely become and new modality for other advanced solid tumors.

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Speaker Details
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    University of Washington, USA
Tumor Treating Fields - A New Modality for Local Tumor Control

7th November 2020,12:00pm

Events of the Speaker
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Past
November 7, 2020
The highlights for the 7th HKIOS include application of artificial intelligence in radiotherapy planning and biomarkers discovery, ultra-high dose rate (FLASH) radiotherapy and alternating electric fields (tumour treating fields or TTF). Many oncologists are not familiar with these brand-new modalities, which are being slowly incorporated into our clinical practice. Due to Covid-19 pandemic, we shall conduct our symposium virtually. We thank our local and overseas speakers for their stern support and contribution again.
Past
October 26, 2019
The 6th Hong Kong International Oncology Symposium (6th HKIOS) was conducted in Sheraton Hong Kong Hotel & Towers on 26th and 27th October. The event was joined by renowned speakers with a higher international representation, reflecting our initiatives in fostering international medical collaborations. Some emerging topics such as artificial intelligence, immunotherapy and radiotherapy were discussed in the symposium.